{"id":94648,"date":"2026-01-26T22:24:06","date_gmt":"2026-01-26T22:24:06","guid":{"rendered":"https:\/\/ikimisli.tr\/?p=94648"},"modified":"2026-01-26T22:24:06","modified_gmt":"2026-01-26T22:24:06","slug":"saglikli-yaslanmak-icin-ilk-adiminiz-d-vitamini-olsun","status":"publish","type":"post","link":"https:\/\/ikimisli.tr\/index.php\/2026\/01\/26\/saglikli-yaslanmak-icin-ilk-adiminiz-d-vitamini-olsun\/","title":{"rendered":"Sa\u011fl\u0131kl\u0131 ya\u015flanmak i\u00e7in ilk ad\u0131m\u0131n\u0131z D vitamini olsun"},"content":{"rendered":"

S\u00d6ZC\u00dc TV Genel Yay\u0131n Y\u00f6netmeni \u0130pek \u00d6zbey, uzmanl\u0131k alan\u0131 biyokimya olan Dr. Ay\u015feg\u00fcl \u00c7oruhlu ile sa\u011fl\u0131kl\u0131 uzun \u00f6mr\u00fcn s\u0131rlar\u0131n\u0131 (longevity) konu\u015fmaya devam ediyor\u2026 <\/p>\n

Dr. Ay\u015feg\u00fcl \u00c7oruhlu, bu defa \u201cmolek\u00fcler ya\u015flanmay\u0131\u201d anlatt\u0131. Bir de vitaminlerin ve antrenman\u0131n longevity ile alakas\u0131na de\u011findi. \u0130\u015fte a\u00e7\u0131klamalar\u0131:<\/p>\n

<\/p>\n

Ya\u015flanma i\u015fini \u00e7\u00f6zme olas\u0131l\u0131\u011f\u0131m\u0131z \u00e7ok y\u00fcksek<\/strong><\/p>\n

Baz\u0131 be\u015ferler \u201cUzun ya\u015fasam ne olacak? Ben sa\u011fl\u0131kl\u0131 olay\u0131m, uzunlu\u011fu k\u0131ymetli de\u011fil\u201d diyor. Ben bu noktada \u015funu s\u00f6ylemek istiyorum: Burada gaye esasen senin ya\u015fayaca\u011f\u0131n \u00f6mr\u00fc, evet bir \u00f6l\u00e7\u00fc uzatmaya (bilimin el verdi\u011fince) gayret g\u00f6sterece\u011fiz ancak esasen as\u0131l husus, ya\u015fad\u0131\u011f\u0131n hayat\u0131n sa\u011fl\u0131kl\u0131 k\u0131sm\u0131n\u0131 uzatmak\u2026<\/p>\n

Biz buna \u201chealth span\u201d (sa\u011fl\u0131kl\u0131 \u00f6m\u00fcr s\u00fcresi) diyoruz. <\/p>\n

\u2018Sa\u011fl\u0131kl\u0131 olma\u2019 vurgusu<\/strong><\/p>\n

E\u011fer longevity ya da uzun sa\u011fl\u0131kl\u0131 \u00f6m\u00fcr diyorsak, sa\u011fl\u0131kl\u0131 k\u0131sm\u0131n\u0131 bilhassa vurguluyoruz.
Molek\u00fcler ya\u015flanmaya gelince; hani seveni var sevmeyeni var lakin sonu\u00e7ta Elon Musk\u2019\u0131n da bu t\u00fcrl\u00fc bir durumu var ya; bizim d\u00fcnyada de\u011fil lakin kendince bir projeksiyon yap\u0131yor gelecekle ilgili… <\/p>\n

Benim bildi\u011fim daha yeni, bu ya\u015flanma i\u015fini \u00e7\u00f6zme olas\u0131l\u0131\u011f\u0131m\u0131z \u00e7ok y\u00fcksek…<\/p>\n

H\u00fccresel de\u011fil art\u0131k molek\u00fcler s\u0131hhati konu\u015fabiliriz<\/strong><\/p>\n

\u00c7\u00fcnk\u00fc bunun sebebi bulununca onu \u201chack\u201dleyecek biyolojik, biyoteknolojik form\u00fcller m\u00fcmk\u00fcn. B\u00fct\u00fcn bilim insanlar\u0131 n\u0131n asl\u0131nda bu t\u00fcrl\u00fc bir s\u0131k\u0131nt\u0131s\u0131 vard\u0131. Bunun ismi \u201cGeroscience\u201d (Ya\u015fl\u0131l\u0131k Bilimi) idi fakat \u015fu anda ya\u015fl\u0131l\u0131k bilimi ya\u015flanm\u0131\u015flarla ilgilenirken, o bu tarafa geldi, ismi Longevity oldu. Gen\u00e7lerle de ilgileniyor ki oraya gitmesin! Ve bunun molek\u00fcler seviyede; h\u00fccre, h\u00fccre i\u00e7i, hatta h\u00fccre i\u00e7indeki atom alt\u0131 par\u00e7ac\u0131klar \u00fczerinden bile manip\u00fcle edilebilirli\u011fi var ve bunlar art\u0131k bilimin bir kesimi. O y\u00fczden h\u00fccresel de\u011fil, molek\u00fcler s\u0131hhati bile konu\u015fabiliriz\u2026<\/p>\n

\u00d6rnek; g\u00fcne\u015f \u0131\u015f\u0131\u011f\u0131n\u0131n benim cildime vurmas\u0131 asl\u0131nda molek\u00fcler seviyede bedenimdeki bir molek\u00fcl\u00fcn fizik\u00ee hareketini de\u011fi\u015ftirdi\u011fi i\u00e7in bana vitamin D yolunu a\u00e7\u0131yor. Asl\u0131nda bir biyoloji, molek\u00fcl \u00fcst\u00fcnden neredeyse \u0131\u015f\u0131ktan gelerek, kimya bile de\u011fil, fotonlar \u00fcst\u00fcnden bende bir \u015fey yap\u0131yor. \u0130\u015fte bu kadar tatl\u0131, nazik detaylar var\u2026<\/p>\n

Yol haritan\u0131z<\/strong><\/p>\n

\u2018\u2019Ben sa\u011fl\u0131kl\u0131 ve uzun ya\u015famak i\u00e7in hangi molek\u00fclden ba\u015flayay\u0131m\u2019\u2019 diyorsan\u0131z\u2026 NAD\u2019lar, NR\u2019lar bir s\u00fcr\u00fc \u015fey var… Evvel vitamin D\u2019den ba\u015flay\u0131n! <\/p>\n

Onu \u00f6l\u00e7t\u00fcrmek s\u0131hhat oca\u011f\u0131nda bile kolay. 50\u2019nin alt\u0131ysa g\u00fcnde i\u015fte 5 bin \u00fcniteye kadar alabilirsiniz.<\/p>\n

Ham maddeyi biz veriyoruz <\/strong><\/p>\n

E\u011fer bir vitamin D dayana\u011f\u0131 al\u0131yorsan\u0131z, bunun hepsi asl\u0131nda orjinal vitamin D de\u011fildir, onun \u00f6nc\u00fcl\u00fcd\u00fcr. Yani asl\u0131nda bedende \u00e7al\u0131\u015fan, b\u00f6brekten \u00e7\u0131km\u0131\u015f molek\u00fcld\u00fcr. Yani ham maddeyi biz veriyoruz. Art\u0131k ham husus olarak g\u00fcne\u015ften, besinden yahut dayanaklardan geldi; onun karaci\u011fer ve b\u00f6brek yolu var.<\/p>\n

\u00c7ok de\u011ferli bir molek\u00fcl<\/strong><\/p>\n

Vitamin D konusunu Covid\u2019den beri \u00f6\u011frendik fakat gere\u011fince de\u011fil. Neden \u00f6\u011frenmedik? \u0130\u015fte biraz imm\u00fcnitede (ba\u011f\u0131\u015f\u0131kl\u0131k), biraz osteoporozda (kemik erimesi) kald\u0131k . O kadar \u00e7ok resmi de\u011fi\u015ftiren bir molek\u00fcl ki bu…<\/p>\n

\u2018\u2019Ben Longevity yapmak istiyorum\u201d diyenin \u015f\u00f6yle demesi l\u00e2z\u0131m: Bu i\u015fin % 70\u2019i sizin yapt\u0131klar\u0131n\u0131z, bir \u015fey almak, a\u011fz\u0131ndan yahut bir teste bakmak isterseniz de bu i\u015fin neredeyse % 40\u2019\u0131n\u0131 vitamin D olu\u015fturuyor. Zira \u00e7al\u0131\u015fmalarda \u201call-cause mortality\u201d (herhangi bir sebepten \u00f6lme ihtimali) oran\u0131n\u0131 % 40 ileri geri de\u011fi\u015ftirebilecek bir molek\u00fclden bahsediyoruz.<\/p>\n

Her ta\u015f\u0131n alt\u0131ndan \u00e7\u0131k\u0131yor<\/strong><\/p>\n

D vitamininin kemikte, ba\u011f\u0131\u015f\u0131kl\u0131kta de\u011feri biliniyor… Ancak bu i\u015fler art\u0131k molek\u00fcler seviyede \u00f6l\u00e7\u00fcld\u00fc\u011f\u00fc i\u00e7in, vitamin D\u2019nin bedendeki yola\u011f\u0131n\u0131 takip edebiliyorsunuz. B\u00f6brekte yaln\u0131zca kalsiyum, kemik de\u011fil; bir bak\u0131yorsun b\u00fct\u00fcn h\u00fccrelerin \u00e7ekirde\u011finde vitamin D\u2019yi bekleyen \u201cVitamin D Resept\u00f6rleri\u201d var! Onlar ba\u011flan\u0131rsa ne oluyor? Epigenetik olarak beden b\u00fcsb\u00fct\u00fcn de\u011fi\u015fiyor; uyguna de, berbata de gidebiliyor, inflamasyonu (iltihab\u0131) azaltabiliyor da… \u00d6l\u00e7\u00fcs\u00fcne ba\u011fl\u0131 olarak her ta\u015f\u0131n alt\u0131ndan \u00e7\u0131kt\u0131klar\u0131 i\u00e7in molek\u00fclerden ba\u015flad\u0131k, benim okudu\u011fum bahse geldik. Oradan da Longevity d\u00fcnyas\u0131n\u0131n ve vitamin D d\u00fcnyas\u0131n\u0131n k\u00fc\u00e7\u00fck bir eksi\u011fini tamamlamak \u00fczereyiz<\/p>\n

G\u00fcne\u015f yetmez karaci\u011fer ve b\u00f6breklerin uygun olmas\u0131 l\u00e2z\u0131m<\/strong><\/p>\n

Vitamin D\u2019nin farkl\u0131 sebeplerden herkeste t\u0131pk\u0131 yap\u0131lamamas\u0131 var. Diyelim ki herkesin genetik kapasitesi birebir, sorun yok. Ancak asl\u0131nda g\u00fcnd\u00fcz g\u00fcne\u015fe az \u00e7\u0131k\u0131yoruz. Yaz devrinde biraz alabiliyorsak bile k\u0131\u015f\u0131n i\u00e7erideyiz. \u00d6rne\u011fin daha s\u0131cak \u00fclkelerde g\u00fcne\u015f \u00e7ok var ancak onlar\u0131n da vitamin D\u2019si d\u00fc\u015f\u00fck; zira i\u00e7eride ya\u015f\u0131yorlar ki yaz\u0131n biz de \u00f6yleyiz; ofisteyiz vesaire… <\/p>\n

Bir tane daha maj\u00f6r sorun var: Herkesin karaci\u011feri uygun olmal\u0131 ki benim g\u00fcne\u015ften gelen vitamin D\u2019nin bir karaci\u011fer dura\u011f\u0131n\u0131n g\u00fczel olmas\u0131 l\u00e2z\u0131m, bir b\u00f6brek dura\u011f\u0131n\u0131n g\u00fczel olmas\u0131 l\u00e2z\u0131m. Olmazsa, o yola ge\u00e7emezse ham unsur daha az oluyor. \u00c7ok suplement var eczanede, \u00e7ok bilgi var, o var bu var… Sa\u011fl\u0131k ocaklar\u0131nda, iki ayda bir D Vitamini bak\u0131labiliyor. Bak\u0131lacak; 50\u2019nin alt\u0131ysa onu desteklemek gerekiyor. <\/p>\n

ORGAN\u0130K BESLENSEN\u0130Z DE KARAC\u0130\u011eER\u0130N\u0130Z YA\u011eLIYSA YARARI OLMAZ<\/strong><\/span><\/p>\n

Karaci\u011fer bizim pakl\u0131k filtremiz ya yiyecekler oradan ge\u00e7ecek \u00fczere d\u00fc\u015f\u00fcn\u00fcn. Hani \u2018\u2019eledim eledim tekrar de pestisit vard\u0131r ancak zerzevat \u00fczere d\u00fczg\u00fcn bir \u015fey yiyeyim\u2019\u2019 diyebiliriz. Karaci\u011feri al\u0131\u015f\u0131lm\u0131\u015f alkol de bozar, organik yemek de laz\u0131m falan… Fakat \u201cKaraci\u011fer ya\u011flanmas\u0131 d\u00fcnyan\u0131n sorunu.\u201d Senin karaci\u011ferin ya\u011fl\u0131 demek; o ya\u011f karaci\u011ferin i\u00e7inde, asl\u0131nda zehirden ar\u0131nd\u0131rma yapacak h\u00fccrelerin i\u00e7inde duruyor demek. Yani pakl\u0131k fabrikas\u0131nda \u00e7al\u0131\u015facak alan azal\u0131yor; zira i\u00e7i ya\u011fla birikmi\u015f oluyor. Demek istedi\u011fim; karaci\u011fer ya\u011flanmas\u0131, \u2018ben \u00e7ok organik yiyorum\u2019 desen de asl\u0131nda senin i\u00e7in bir sorun. Evvel karaci\u011fere bakmak laz\u0131m; ya\u011fl\u0131 m\u0131 de\u011fil mi diye\u2026 <\/p>\n

Bal\u0131k yemenin sa\u011fl\u0131kl\u0131 oldu\u011funu biliyorum fakat ben bal\u0131k yiyorum diye Omega-3 almamay\u0131 ben kendim yapmam. Bence vitaminler, takviyeler b\u00fcy\u00fck bir husus olacak zira i\u015fte yiyecekler sa\u011fl\u0131kl\u0131 m\u0131, i\u015flenmi\u015f mi, do\u011fal\u0131 var m\u0131 falan filan diye d\u00fcnya b\u00fcy\u00fcd\u00fck\u00e7e muhta\u00e7l\u0131klar\u0131 mecburen g\u00fczel olan bir eserle yerine koyma u\u011fra\u015f\u0131m\u0131z\u0131n s\u0131hhatte yeri var, longevity\u2019de elbette yeri var.<\/p>\n

Kemiklerinizi hareketle uyar\u0131n<\/strong><\/p>\n

Hareket nereden tutsan i\u015fe yar\u0131yor. Bir \u00f6rnek vereyim; i\u015fte osteoporoz, kemik falan konu\u015fuyoruz de\u011fil mi, Vitamin D\u2019yi de oraya ba\u011flad\u0131k… <\/p>\n

Yer\u00e7ekiminin yani ayaklar\u0131 yere vurma hareketinin yaratt\u0131\u011f\u0131 \u00fcste yanl\u0131\u015fs\u0131z vibrasyon (titre\u015fim), kemikte mekanik bir ihtarla kemik \u00fcretimini art\u0131ran bir \u015feydir. Bunun en kolay \u00f6rne\u011fi ayakkab\u0131 topu\u011funuzu vurunca topu\u011funuzun gerisinde bombe olur de\u011fil mi? \u0130\u015fte bu k\u00fc\u00e7\u00fck darbelerin uyarmas\u0131 yla olur.Y\u00fcr\u00fcyor olmak da asl\u0131nda kemik s\u0131hhatine ba\u011fland\u0131. Kas ve kalp s\u0131hhatine asl\u0131nda ba\u011flan\u0131r… O y\u00fczden en kolay\u0131; birinci lokmadan sonra 50. dakika, biraz m\u00fczik, bir merdiven, \u00fcst kata \u00e7\u0131k alt kata in, biraz hopla z\u0131pla, k\u0131m\u0131ldama sa\u011flar.<\/p>\n

AZ YEMEK \u0130Y\u0130D\u0130R<\/strong><\/span><\/p>\n

Gelelim NAD\u2019lara\u2026 <\/p>\n

Gen\u00e7lik ve g\u00fc\u00e7 kayna\u011f\u0131 olarak tan\u0131mlanan bu molek\u00fcl, bedenimizde h\u00fccresel yenilenme i\u00e7in kritik bir rol oynuyor. Art\u0131k molek\u00fcler ya\u015flanmay\u0131 bulma d\u00fcnyas\u0131n\u0131n geldi\u011fi noktalardan biri bu. Mesela karaci\u011fer organ, karaci\u011fer h\u00fccresinin i\u00e7inde de bir \u015fey var o da h\u00fccrenin i\u00e7 organeli. Bu o da de\u011fil! Bu bu t\u00fcrl\u00fc en k\u00fc\u00e7\u00fcc\u00fck kofakt\u00f6r, mikro bir molek\u00fcl. Bu molek\u00fcl\u00fc beden g\u00f6rd\u00fc\u011f\u00fcnde \u015f\u00f6yle d\u00fc\u015f\u00fcn\u00fcyor \u201cBen iki \u015fey yapm\u0131\u015f olabilirim; bu \u00e7oksa… Ya a\u00e7\u0131md\u0131r ya az yemi\u015fimdir ya da \u00e7ok k\u0131m\u0131lday\u0131p \u00e7ok g\u00fc\u00e7 harcam\u0131\u015f\u0131md\u0131r.\u201d Bunu fark ettik. <\/p>\n

Yani ben ko\u015funca yiyecek azald\u0131\u011f\u0131n\u0131 o denli anl\u0131yor yahut ben a\u00e7 kal\u0131nca yiyece\u011fin azald\u0131\u011f\u0131n\u0131 benim midem guruldad\u0131\u011f\u0131 i\u00e7in h\u00fccre anlam\u0131yor; bu artt\u0131\u011f\u0131 i\u00e7in anl\u0131yor! O vakit neye geliyoruz? Az yemek iyidir\u2026<\/p>\n

Yemek vakti da \u00f6nemli<\/strong><\/p>\n

Vitamin D\u2019ye b\u00fcy\u00fck bir mana y\u00fckledik ya, ondan daha da b\u00fcy\u00fck mana y\u00fckleyece\u011fimiz \u015fey; \u00e7ok fazla yememek. Bana nazaran ak\u015fam a\u00e7l\u0131\u011f\u0131 lakin literat\u00fcr buna genel olarak \u201ckaloriyi azalt\u201d diyor. A\u00e7l\u0131k vakti, yani ne vakit yemedi\u011fin yedi\u011finden m\u00fchime geliyor bu d\u00fcnyada. Bedenin anlad\u0131\u011f\u0131 bu! Bunu g\u00f6r\u00fcnce \u201cA a\u00e7\u0131m! Ya da \u00e7ok k\u0131m\u0131ldad\u0131m yani materyalim yok\u201d anl\u0131yor.<\/p>\n

V\u00fccut yenileniyor<\/strong><\/p>\n

V\u00fccut \u201cMadem a\u00e7\u0131m; benim \u015fu anda yedekli davranmam laz\u0131m, \u00e7abucak hayatta kalma B plan\u0131\u2026 Kurallar yeterli olana kadar DNA\u2019m\u0131\u2019\u2019 diyor. M\u00fcnasebetiyle NAD\u2019\u0131n ittirdi\u011fi birtak\u0131m i\u015fte \u201cSirtuin\u201d diye yaz\u0131l\u0131yor genler var; o genler DNA\u2019y\u0131 m\u00fcdafaaya al\u0131yorlar.
Peki DNA\u2019n\u0131 korudun lakin gere\u00e7 yok ne yapacaks\u0131n? O vakit benim bedende ne kadar \u00e7ar\u00e7\u00f6p varsa; (karaci\u011ferde, kal\u00e7ada ya\u011f m\u0131 var? Eski h\u00fccreler mi var?) \u2018\u2019Onlar\u0131 \u00e7abucak bir onaray\u0131m..\u2019\u2019 <\/p>\n

Biz onlar\u0131 zombi diye adland\u0131r\u0131yoruz- daha T\u00fcrk\u00e7esi \u2018\u2019B\u00fct\u00fcn eski h\u00fccreleri \u015f\u00f6yle bir devridaim edeyim oradan gere\u00e7 \u00e7alay\u0131m bari\u2019\u2019 diyor. A\u00e7 kal\u0131nca, beden bunu g\u00f6r\u00fcnce bizim a\u00e7l\u0131\u011f\u0131m\u0131z\u0131 eski h\u00fccrelerden kurtularak, bizi bir \u00e7e\u015fit m\u00fcdafaaya alarak \u00f6d\u00fcllendiriyor. A\u00e7l\u0131k \u00f6d\u00fcl\u00fcn\u00fcn h\u00fccredeki kar\u015f\u0131l\u0131\u011f\u0131 bu. <\/p>\n","protected":false},"excerpt":{"rendered":"

\u201cBen uzun ya\u015famak, Longevity yapmak i\u00e7in hangi molek\u00fclden ba\u015flayay\u0131m?\u2019\u2019 diyorsan\u0131z \u00f6nceli\u011finiz D vitamini olsun. Onu s\u0131hhat oca\u011f\u0131nda bile \u00f6l\u00e7t\u00fcrebilirsiniz. \u015eayet pahas\u0131 50\u2019nin alt\u0131ysa destek al\u0131n.<\/p>\n","protected":false},"author":1,"featured_media":94649,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29],"tags":[3335,2150,10020,516,10019],"class_list":["post-94648","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-hucre","tag-karaciger","tag-molekuler","tag-saglikli","tag-vitamin-d"],"_links":{"self":[{"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/posts\/94648","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/comments?post=94648"}],"version-history":[{"count":1,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/posts\/94648\/revisions"}],"predecessor-version":[{"id":94651,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/posts\/94648\/revisions\/94651"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/media\/94649"}],"wp:attachment":[{"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/media?parent=94648"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/categories?post=94648"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ikimisli.tr\/index.php\/wp-json\/wp\/v2\/tags?post=94648"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}